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STARTUP FLASH - July 19, 2025

Hadrian Secures $260M Series C to Scale AI-Driven Defense Manufacturing

TOP 3 STORIES:
1. Hadrian Raises $260M to Expand Automated Defense Factories
Hadrian, a California-based startup, closed a $260 million Series C round to accelerate its AI-powered manufacturing for aerospace and defense, including a new Arizona facility and expanded California operations[1]. This signals robust investor appetite for deeptech and defense automation, offering founders in industrial AI and advanced manufacturing a clear path to scale with strong venture backing[1].

2. OpenEvidence Closes $210M Series B for Clinical AI Platform
OpenEvidence, a Cambridge healthtech startup, landed $210 million in Series B funding to enhance its AI-driven medical search platform, now used by a significant share of U.S. clinicians[1]. The deal highlights the growing demand for AI tools in healthcare, encouraging founders to focus on clinical utility and hospital adoption for rapid market traction[1].

3. KoBold Metals Raises $537M to Accelerate AI-Driven Mineral Exploration
KoBold Metals, leveraging AI for critical mineral discovery, secured $537 million in Series C funding to fuel its mission of sourcing essential materials for renewable energy and EVs[3]. This underscores the strategic importance of climate tech and resource innovation, with opportunities for startups addressing supply chain resilience and sustainability[3].

Flash Insight:
AI and automation continue to dominate startup funding, with major rounds in defense, healthcare, and climate tech reflecting investor confidence in sectors with high barriers to entry and urgent market needs. Founders should note the premium on platforms that combine deep technology with clear, large-scale applications—especially where regulatory or infrastructure complexity creates defensible moats. As capital concentrates in these high-impact verticals, early-stage startups can differentiate by targeting niche problems within these broader trends, building toward scalable solutions that attract both customers and top-tier investors.

Sources:
[1] https://techstartups.com/2025/07/18/top-startup-and-tech-funding-news-roundup-for-the-week-ending-july-18-2025/
[3] https://forgeglobal.com/insights/startup-trends-top-funding-rounds-of-q1-2025/

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