Startup Flash Report

STARTUP FLASH - October 21, 2025

OpenEvidence Raises $200M at $6B Valuation to Bring Verified AI to Clinicians

TOP 3 STORIES:
1. OpenEvidence, an AI-powered clinical decision platform, has secured $200 million in new funding at a $6 billion valuation, aiming to deploy "ChatGPT for doctors" in hospitals worldwide. This signals a major leap for AI in healthcare, offering founders in healthtech a clear path to scale validated, regulatory-compliant AI products for critical industries[9].

2. Tubulis, a German biotech startup, raised $361 million in Series C to advance its antibody-drug conjugate (ADC) pipeline for cancer treatment. Despite a broader downturn in oncology investment, this round demonstrates that breakthrough science and strong clinical data can still attract significant capital, encouraging biotech founders to focus on differentiated, high-impact therapies[4].

3. 1001 AI, a deeptech startup based in London and Dubai, closed a $9 million seed round to launch an AI-native operating system for automating decision-making in aviation, logistics, and construction across the Gulf. This move highlights the growing appetite for vertical AI solutions in traditional industries, suggesting founders should target sectors with large inefficiencies and regulatory complexity[2].

Flash Insight:
AI-driven innovation continues to dominate funding headlines, with both horizontal (OpenEvidence) and vertical (1001 AI) solutions attracting major capital. The outsized Tubulis round, despite a tough biotech market, shows that investors are still willing to back startups with clear clinical differentiation and market potential. For founders, the current environment rewards deep tech, regulatory readiness, and a focus on real-world impact—especially in sectors where AI and automation can unlock new value.

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Sources:

[1] Recent funding rounds - October 2025 - Seedtable
https://www.seedtable.com/funding-rounds/recent

[2] 1001 AI closes $9 million seed round to accelerate GCC landing - Wamda
https://www.wamda.com/2025/10/1001-ai-closes-9-million-seed-round-accelerate-gcc-landing

[4] Cancer drug startup Tubulis raises $361 million for ADCs - BioPharma Dive
https://www.biopharmadive.com/news/tubulis-adcs-antibody-drug-conjugate-series-c-esmo-2025/802753/

[9] ChatGPT for doctors? OpenEvidence scoops $200M at $6B to bring verified AI to clinicians - Tech Funding News
https://techfundingnews.com/openevidence-chatgpt-for-doctors-raises-200m-6b-valuation/